As an editor you want to have your CDN being updated immediately after publishing a new story. If you use Varnish or Akamai as a CDN today there is no real good support for this. There is support for HTTP purge in eZ Flow today but this needs to be improved as well as adding support for Akamai Purge.
We should at the same time look into a proper mechanism to track all pages an object is displayed (storing while rendering the page templates?). In that way you can easily know all pages where an object is displayed so that we can guarantee that the CDN updates are correct. Smart cache is good, but in many cases too complex to configure this correct.
Example of Akamai purge in PHP at the bottom of this post:http://bugs.php.net/bug.php?id=43910
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